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In the existing review we have verified that maintenancetype DNA methyltransferase Dnmt1 scarcely methylates hemihydroxymethylated DNA utilizing highly purified Dnmt1 [28] (Figure 1A). In addition, we have shown that hemi-methylated DNA binding domain SRA of Uhrf1, which is a prerequisite localized in all the examined regions the place 5hmC was enriched (Figure 6A), although Dnmt1 was not signifi
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